ANC Workshop - Kashyap Chhatbar
Tuesday, 21st March 2023
Interpretable linear and non-linear models predict gene expression from histone modifications
Abstract: Mammalian epigenome influence multiple key biological processes including tissue differentiation and development. It is experimantally characterized by numerous quantifications at basepair resolution. We apply Supervised Principal Component Analysis (SPCA) and Kernel SPCA to model this high-dimesional input data and predict gene expression output. Furthermore, we utilise simple Taylor decomposition to make model-specific biological inferences.
Event type: Workshop
Date: Tuesday, 21st March 2023
Speaker(s): Kashyap Chhatbar
Chair/Host: Cian Eastwood